Tag: technical

Human renal cell carcinoma - Vimentin antibody

Vimentin Antibody Validated

by Histology Reference Guide, posted in FFPE tissues, histology service, IHC

We have been working hard to validate many new antibodies for research use.  Vimentin is now available for use on Human, mouse and rat FFPE tissues.

According to the data sheet Vimentin, is a general marker of cells originating in the mesenchyme. Vimentin is frequently co-expressed with other members of the intermediate filament family, such as the cytokeratins, in neoplasms including melanoma and breast carcinoma.

Human colon – Vimentin Antibody
Human renal cell carcinoma – Vimentin antibody
Human lung – Vimentin antibody
Human normal kidney – Vimentin antibody
Human colon – Vimentin antibody
Human melanoma – Vimentin antibody
Human Liver – Vimentin antibody

Abnormal Tissue Identification

by Histology Reference Guide, posted in H&E, Histology, histology service, histology slides, IHC

For us in histology, normal tissue identification is typically an easy process.  As histologists, we were once required to identify all normal tissues by H&E under the microscope.

For abnormal tissue however, an H&E stained slide can be very difficult to identify tissue type and diagnosis.  That’s why when a pathologist orders multiple stains on one tissue, they are trying to get a larger picture to understand its etiology.

To help in understanding, here are 3 stains on the same tissue, H&E, SMA, & CD8 at 4x & 10x.  This is human tissue.  Can you identify this tissue and its diagnosis?

 

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I’ll give you choices.

A. Lung – Spindle cell carcinoma

B. Liver – Cirrhosis

C. Colon – Adenocarcinoma

D. Heart – Myocardial fibrosis

 

Small Business Histology

by Histology Reference Guide, posted in histology service

Come experience our extremely skilled and experienced technical team to show what your experiment results could look like.    Try us today.

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