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Beta-Catenin Staining

Mouse testicle CTNNB1

We offer many antibody staining services, like working up protocols for unknown antibodies. This was the case for the Beta-Catenin (CTNNB1) antibody from Biolegend.

Our Beta-catenin antibody works in human, mouse and rat tissues.  Both normal and abnormal tissues exhibit positive staining.

 

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Colon Adenocarcinoma

Colon Cancer

Pathology of colon cancer as seen through the eyes of a histologist.  How many different ways are there to visualize cancer?  The more the better!

Hematoxylin & Eosin (our recipe)

HMGB1 Antibody – According to the The Human Protein Atlas HMGB1 protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration.

CD8 Antibody in the Human Protein Atlas ( CD8A) describes it as a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system.

Indoleamine Antibody – This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity (IDO1).

Perforin Antibody – This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis (Perforin).

Colon cancer
Colon Adenocarcinoma Perforin Antibody

 

Note: All tissues were bought, cut and stained at Histologistics Inc as positive control slides.  These are not part of any study.

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Antibody Discoveries Customized for You

If you need immunohistochemistry for your project, we have years of experience working with both known and unknown antibody protocols.  We can get your project done fast with great results at a fraction of the price.  Call or email us today!

Picture of Mouse Stomach - Antibody HMGB1
Mouse Stomach – Antibody HMGB1
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How To Detect Alzheimer’s Disease Using Histology

 Dave Adams and Ben Snyder created the first transgenic mouse model in 1995. Histology played a role in the detection of the amyloid plaques surrounded by dystrophic neurites, and show profound synaptic loss, neurofibrillary tangle formation and gliosis.  The beta amyloid and Tau proteins are detected by antibodies used in immunohistochemistry. There are a whole host of different special stains for neuroglia, astrocytes, myelin sheath, neurofibril tangles and senile plaques.  The Bielschowsy stain shows neurofibrils and senile plaques black while the background is yellow-brown.

http://www.nature.com/nature/journal/v373/n6514/abs/373523a0.html

Beilschowsky Special Stain on Mouse Brain For Neurofibrils and Senile Plaques 20x
Beilschowsky Special Stain on Mouse Brain For Neurofibrils and Senile Plaques 20x

 

 

 

 

 

An Expert Histology Service