A comparison of the picrosirius red stain with and without a nuclear stain.

We took the original picrosirius red stain and modified it to create our version with crisp looking nuclei.

The picture on the left has been stained with Weigert’s hematoxylin and on the right, no nuclear stain.

Collagen – Red         Muscle – Green       Nuclei – black

 

What is your preference?

Collagen – the tissue glue, plays a vital role in maintaining structural integrity in tissue function.  This stain is used to detect many disease models such as liver fibrosis, skin wounds, myocardial scars, and arterial tissue.